Angiotensin-Converting Enzyme Inhibitor Ramiprilat Interferes With the Sequestration of the B ₂ Kinin Receptor Within the Plasma Membrane of Native Endothelial Cells

Abstract

The ACE inhibitor ramiprilat interferes with the targeting of the B2 kinin receptor to CR membrane domains in native endothelial cells. Therefore, effects other than the inhibition of kininase II may account for the effects of ramiprilat and other ACE inhibitors on the vascular system.