<i>TCF7L2</i>Gene Polymorphisms Confer an Increased Risk for Early Impairment of Glucose Metabolism and Increased Height in Obese Children

Abstract

Our data indicate for the first time that TCF7L2 gene variants confer an increased risk for early impairment of glucose metabolism in obese children, which is consistent with adult studies identifying TCF7L2 as a major diabetes susceptibility gene.