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Ectopic expression of a T-box transcription factor, eomesodermin, renders CD4+ Th cells cytotoxic by activating both perforin- and FasL-pathways

InflammationT-box Transcription FactorAutoimmune DiseaseEctopic ExpressionT-regulatory CellApoptosisImmune RegulationImmunologyCell DeathAutoimmunityCellular Immune ResponseImmunopathologyMedicineCell BiologyCell Signaling