Chronic Granulocytic Leukaemia with Ph¹ Negative Cells in Bone Marrow and a Ten Year Remission after Busulphan Hypoplasia

Abstract

Summary. Following busulphan‐induced bone marrow insufficiency a patient with chronic granulocytic leukaemia has had a remission lasting 10 yr. During this time repeated chromosome studies on bone marrow have shown the persistence of a majority of Ph 1 negative cells. The relationship of this finding to the unusually long remission is discussed.