MedicineNephrologyUrologyHemodynamic ManagementRenal PathophysiologyVascular SurgeryBlood Pressure ManagementHypertension ManagementRenal Artery DiseaseRenal DiseaseRenal Vascular DiseaseRenovascular Hypertension EvaluationDemographic Data ExtractionDemographic Pattern Analysis
The Cooperative Study of Renovascular Hypertension is a multicenter investigation that documents its aims, organization, diagnostic protocols, statistical methods, and demographic characteristics. The study aims to establish prospective definitions of renovascular hypertension and provide an objective basis for its diagnosis and treatment. The study employed a decentralized, multidisciplinary design with specialized groups for data analysis and refinement. Among 2,442 participants, 1,128 had primary hypertension, 880 had renovascular disease, 355 had parenchymal kidney disease, and 79 had miscellaneous disorders; 577 operations were performed on 502 renal arterial disease patients, and 384 patients had at least one year of postoperative follow‑up.
This report on the Cooperative Study of Renovascular Hypertension, includes details of its purposes, organization, diagnostic studies, statistical methodology, and demographic data. Of 2,442 patients studied, 1,128 subjects were judged to have primary (essential) hypertension, 880 renovascular disease, 355 parenchymal kidney disease, and 79 miscellaneous disorders. There were 577 operative procedures in 502 patients with renal arterial disease. There were 384 patients with follow-up of at least one year postsurgery. A unique aspect of this multidisciplinary cooperative study was its decentralization into special study groups for analysis and refinement of data. This and subsequent publications should provide prospective definitions of "renovascular hypertension," as well as an objective basis for the diagnosis and treatment of this condition.