Current Oncology · 2009 · 15 citations · 15 references
DentistryOral BiologyOral PathologyCancer PreventionOral MicrobiologyOral OncologyOral Cancer EpidemiologyOral Cancer PathologyOral Cancer PreventionOral CarcinogenesisOral Cavity CancerOral NeoplasiaCannabis AbuseCell Cycle DynamicsCell Division ControlHuman Papillomavirus-associated Oral CancerIndirect Contact TransmissionOral Cancer IncidenceOral Human Papillomavirus InfectionTobacco-related Oral Cancer Risk
Human papilloma virus (HPV) has many known strains, two of the most well studied perhaps being the high-risk types 16 and 18. These strains have attracted more interest because they are known to disrupt tumour-suppressor genes that control the cell cycle, rendering those genes less effective at keeping cell division in check.Within the last decade, an increase in oral hpv-linked cancers of the throat and tongue has been attributed to exposure and contraction of hpv through oral sex, most notably in younger people. An understudied and arguably equal contributor to oral hpv infection might be indirect contact with an infected person. Presented here is a brief but important perspective on the relationship between cannabis use and oral cancer. The development of oral cancer is not a result of smoking cannabis per se; rather, it is hypothesized to be a result of contracting hpv through various forms of sharing and passing joints and other smoking apparatuses. Therefore, it is hypothesized that bogarting (and not passing) joints might decrease oral hpv among cannabis smokers. Future research should therefore investigate the prevalence of oral hpv in cannabis smokers to better understand its epidemiology.
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Case–Control Study of Human Papillomavirus and Oropharyngeal Cancer
Gypsyamber DʼSouza, Aimée R. Kreimer, Raphael P. Viscidi et al. · New England Journal of Medicine · 2007 · 2.7K citations
Medicine, Oncology, Cancer Control +13
A causal role for human papillomavirus in head and neck cancer
ML Gillison, DR Lowy · The Lancet · 2004 · 225 citations