Bone‐Tissue Formation and Integration of Titanium Implants: An Evaluation with Newly Developed Enzyme and Immunohistochemical Techniques

Abstract

The combination of routine histologic stainings with enzyme and immunohistochemical technique of cut and ground specimens is a valuable tool in the investigations of retrieved implants from humans and animals. This novel technique now may be used to describe the state of bone regeneration in the interface zone associated with implant research.