Effects of montelukast (MK-0476), a new potent cysteinyl leukotriene (LTD4) receptor antagonist, in patients with chronic asthma

Leukotrienes are potent constrictors of human bronchi

Sven‐Erik Dahlén, Per Hedqvist, Sven Hammarström et al. · Nature · 1980 · 972 citations

Medicine, Pharmacology, Physiology +11

Inhibition of arachidonic acid release from cells as the biochemical action of anti-inflammatory corticosteroids.

S L Hong, Lawrence Levine · Proceedings of the National Academy of Sciences · 1976 · 571 citations · Full text

Life Sciences, Biochemistry, Pharmacology +17

Inhibition of Exercise-Induced Bronchoconstriction by MK-571, a Potent Leukotriene D₄–Receptor Antagonist

Patrick Manning, Richard M. Watson, Dorothy J. Margolskee et al. · New England Journal of Medicine · 1990 · 401 citations · Full text

Life Sciences, Pharmacology, Exercise Physiology +8

The Effect of Inhibition of 5-Lipoxygenase by Zileuton in Mild-to-Moderate Asthma

Elliot Israel · Annals of Internal Medicine · 1993 · 367 citations

Pharmacy, Pharmacology, Pharmacotherapy +16

Effects of 6 Weeks of Therapy with Oral Doses of ICI 204,219, a Leukotriene D4 Receptor Antagonist, in Subjects with Bronchial Asthma. ACCOLATE Asthma Trialists Group

S L Spector, Lewis J. Smith, Mitchell Glass · American Journal of Respiratory and Critical Care Medicine · 1994 · 348 citations

Pharmacy, Pharmacology, Pharmacotherapy +11