Gene therapy in a rodent model of Parkinson's disease using differentiated C6 cells expressing a GFAP-tyrosine hydroxylase transgene

Embryonic Stem Cell Lines Derived from Human Blastocysts

James A. Thomson, Joseph Itskovitz‐Eldor, Sander S. Shapiro et al. · Science · 1998 · 15.9K citations

Life Sciences, Cell Biology, Developmental Biology +17

GFAP promoter directs astrocyte-specific expression in transgenic mice

Michael Brenner, WC Kisseberth, Yuan Su et al. · Journal of Neuroscience · 1994 · 497 citations · Full text

Medicine, Genetics, Neuroscience +17

Rapidly progressive autosomal dominant parkinsonism and dementia with pallido‐ponto‐nigral degeneration

Ronald F. Pfeiffer, Mohit Bhatt, Robert L. Schelper et al. · Annals of Neurology · 1992 · 188 citations

Medicine, Neurology, Neuroscience +17

Multiple interacting sites regulate astrocyte-specific transcription of the human gene for glial fibrillary acidic protein.

F. Besnard, Michael Brenner, Y. Nakatani et al. · Journal of Biological Chemistry · 1991 · 147 citations · Full text

Life Sciences, Genetics, Molecular Biology +15

Generation of DOPA-Producing Astrocytes by Retroviral Transduction of the Human Tyrosine Hydroxylase Gene:In VitroCharacterization andin VivoEffects in the Rat Parkinson Model

Cecilia Lundberg, Philippe Horellou, Jacques Mallet et al. · Experimental Neurology · 1996 · 138 citations

Medicine, Neurobiology, Neuroscience +17