Nicotine Exposure and Metabolizer Phenotypes from Analysis of Urinary Nicotine and its 15 Metabolites by LC–MS

Abstract

Using this assay it will now be possible to determine whether there are relationships between nicotine exposure and/or metabolizer phenotype with exposure to toxic substances that are present in tobacco smoke and/or to biological response biomarkers to tobacco smoking. This will help in identifying individuals at high risk for developing smoking-related diseases as well as those amenable to smoking cessation programs.