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Membrane 5α-pregnane-3,20-dione (5αP) receptors in MCF-7 and MCF-10A breast cancer cells are up-regulated by estradiol and 5αP and down-regulated by the progesterone metabolites, 3α-dihydroprogesterone and 20α-dihydroprogesterone, with associated changes in cell proliferation and detachment

Breast OncologyMembrane 5α-Pregnane-3,20-dioneUterine ReceptivityGynecologyCancer Cell BiologyCell ProliferationBreast CancerRadiation OncologyMedicineCell BiologyMammary Gland DevelopmentTumor BiologyEndocrine-related CancerHealth Sciences