Monodisperse, Molecularly Imprinted Polymer Microspheres Prepared by Precipitation Polymerization for Affinity Separation Applications

Abstract

Theophilline-imprinted polymer microspheres were obtained in monodisperse form with diameters of about 5 μm (see picture) in a single synthetic step by precipitation polymerization. This robust material, which proved suitable for use in HPLC, can, in principle, also be applied in any application in which molecular recognition phenomena play a role.