A Multicenter, 14-Week Study of Telmisartan and Ramipril in Patients With Mild-to-Moderate Hypertension Using Ambulatory Blood Pressure Monitoring

Abstract

Telmisartan 80 mg was consistently more effective than ramipril 10 mg in reducing both DBP and SBP during the last 6 h of the dosing interval, a measure of the early morning period when patients are at greatest risk of life-threatening cardiovascular and cerebrovascular events. Telmisartan 80 mg was also more effective than ramipril 10 mg in reducing BP throughout the entire 24-h dosing interval. Both drugs were well tolerated.