Cardiovascular effects of morphine and opioid peptides following intracisternal administration in chloralose-anesthetized rats

Identification of two related pentapeptides from the brain with potent opiate agonist activity

Joel W. Hughes, Terry Smith, H. W. Kosterlitz et al. · Nature · 1975 · 3.8K citations

Medicine, Medicinal Chemistry, Pharmacology +13

Opiates and endogenous opioid peptides

John Kelly, Raymond Dingledine · Trends in Biochemical Sciences · 1977 · 1.3K citations

Medicine, Neuroscience, Pharmacology +12

Immunohistochemical studies using antibodies to leucine-enkephalin: Initial observations on the nervous system of the rat

R. Elde, Tomas Hökfelt, O. Johansson et al. · Neuroscience · 1976 · 774 citations

Medicine, Neurobiology, Neuroscience +9

Isolation and structure of an untriakontapeptide with opiate activity from camel pituitary glands.

C H Li, David Chung · Proceedings of the National Academy of Sciences · 1976 · 637 citations · Full text

Life Sciences, Biochemistry, Pharmacology +17

Central cardiovascular effects of morphinomimetic peptides in dogs

Michel Laubie, Henri Schmitt, M Vincent et al. · European Journal of Pharmacology · 1977 · 245 citations

Medicine, Cardiology, Physiology +12