A new synthesis of α-fluoro-α,β-unsaturated ketones and esters based on organoselenium methodology

Abstract

Fluoroselenenylation of α-diazoketones and α-diazoesters using a phenylselenenyl fluoride equivalent, generated in situ from phenylselenenyl bromide and AgF, followed by oxidation with hydrogen peroxide, provided α-fluoro-α,β-unsaturated ketones and ester, respectively, in moderate yields.