Concepedia

Synthesis of a series of 8-(substituted-phenyl)xanthines and a study on the effects of substitution pattern of phenyl substituents on affinity for adenosine A1 and A2A receptors

Ranju Bansal, Gulshan Kumar, Deepika Gandhi, Louise Young, Alan L. Harvey

European Journal of Medicinal Chemistry · 2008 · 22 citations · 7 references

DOIFull text

Open access

Concepts

References

7

Synthesis of 1-Mono- and 1,3-Di-Substituted 6-Aminouracils. Diuretic Activity

V. Papesch, E.F. Schroeder · The Journal of Organic Chemistry · 1951 · 151 citations

, , +10

1,8-Disubstituted Xanthine Derivatives:  Synthesis of Potent A<sub>2B</sub>-Selective Adenosine Receptor Antagonists

Alaa M. Hayallah, Jesús Sandoval-Ramı́rez, Ulrike Reith et al. · Journal of Medicinal Chemistry · 2002 · 134 citations · Full text

, , +6

Reactions of 1,3-Dimethyl-5,6-diaminouracil

F. F. Blicke, H. C. Godt · Journal of the American Chemical Society · 1954 · 101 citations

, , +4

Preparation, Properties, Reactions, and Adenosine Receptor Affinities of Sulfophenylxanthine Nitrophenyl Esters:  Toward the Development of Sulfonic Acid Prodrugs with Peroral Bioavailability

Yan Luo, Christa E. Müller · Journal of Medicinal Chemistry · 2004 · 98 citations · Full text

, , +13

8-Aryl- and 8-cycloalkyl-1,3-dipropylxanthines: further potent and selective antagonists for A1-adenosine receptors

Mah T. Shamim, D. Ukena, William L. Padgett et al. · Journal of Medicinal Chemistry · 1988 · 47 citations · Full text

, , +10