Specific N-terminal mutations in the human androgen receptor induce cytotoxicity

Targeted gene expression as a means of altering cell fates and generating dominant phenotypes

Andrea H. Brand, Norbert Perrimon · Development · 1993 · 9.8K citations

Life Sciences, Developmental Biology, Genetics +17

Common Structure of Soluble Amyloid Oligomers Implies Common Mechanism of Pathogenesis

Rakez Kayed, Elizabeth Head, Jennifer L. Thompson et al. · Science · 2003 · 4.1K citations

Life Sciences, Biochemistry, Neuroscience +17

Formation of Neuronal Intranuclear Inclusions Underlies the Neurological Dysfunction in Mice Transgenic for the HD Mutation

Stephen W. Davies, Mark Turmaine, Barbara A. Cozens et al. · Cell · 1997 · 2.2K citations · Full text

Life Sciences, Genetics, Neurology +17

A Drosophila model of Parkinson's disease

Mel Β. Feany, Welcome Bender · Nature · 2000 · 2.1K citations

Life Sciences, Neurobiology, Neuroscience +12

Histone deacetylase inhibitors arrest polyglutamine-dependent neurodegeneration in Drosophila

Joan S. Steffan, László Bodai, Judit Pallos et al. · Nature · 2001 · 1.2K citations · Full text

Life Sciences, Molecular Biology, Neuroscience +14