Muscle coenzyme Q10 in mitochondrial encephalomyopathies

A mutation in the tRNALeu(UUR) gene associated with the MELAS subgroup of mitochondrial encephalomyopathies

Yu‐ichi Goto, Ikuya Nonaka, Satoshi Horai · Nature · 1990 · 2.1K citations

Life Sciences, Genetics, Molecular Genetics +11

Spontaneous Kearns-Sayre/chronic external ophthalmoplegia plus syndrome associated with a mitochondrial DNA deletion: a slip-replication model and metabolic therapy.

John M. Shoffner, Marie T. Lott, Alexander S. Voljavec et al. · Proceedings of the National Academy of Sciences · 1989 · 507 citations · Full text

Life Sciences, Genetics, Molecular Genetics +17

Muscle coenzyme Q deficiency in familial mitochondrial encephalomyopathy.

Saburo Ogasahara, Andrew G. Engel, David B. Frens et al. · Proceedings of the National Academy of Sciences · 1989 · 368 citations · Full text

Life Sciences, Biochemistry, Genetics +17

Mitochondrial encephalomyopathy (MELAS): Pathological study and successful therapy with coenzyme Q10 and idebenone

Yuetsu Ihara, Reiko Namba, Shigetoshi Kuroda et al. · Journal of the Neurological Sciences · 1989 · 160 citations

Life Sciences, Neurology, Neuroscience +17

Treatment of Kearns‐Sayre syndrome with coenzyme Q ₁₀

Saburo Ogasahara, Yoshiro Nishikawa, Shiro Yorifuji et al. · Neurology · 1986 · 158 citations

Life Sciences, Biochemistry, Physiology +17