Peroxisome Proliferator-Activated Receptor γ Overexpression Suppresses Growth and Induces Apoptosis in Human Multiple Myeloma Cells

Abstract

Our results indicate that PPARgamma negatively controls multiple myeloma growth and viability in part through inhibition of interleukin-6 production by BMSC. As such, PPARgamma is a viable therapeutic target in multiple myeloma.