6-Aminonicotinamide and Acute Degenerative Changes in the Central Nervous System

Significance of Enzymatically Catalyzed Exchange Reactions in Chemotherapy

Nathan O. Kaplan, Abraham Goldin, Stewart R. Humphreys et al. · Science · 1954 · 96 citations

Medicine, Medicinal Chemistry, Pharmacology +10

6-Aminonicotinamide—a Potent Nicotinamide Antagonist

W J Johnson, J. D. McColl · Science · 1955 · 87 citations

Medicine, Medicinal Chemistry, Pharmacology +7

Pathologic effects of antimetabolites. I. Acute lesions in the hypothalamus, peripheral ganglia, and adrenal medulla caused by 3-acetyl pyridine and prevented by nicotinamide.

Samuel P. Hicks · PubMed · 2003 · 86 citations

Medicine, Neuroscience, Pharmacology +16

PRODUCTION OF NICOTINIC ACID DEFICIENCY WITH 3-ACETYLPYRIDINE, THE KETONE ANALOGUE OF NICOTINIC ACID

D. W. Woolley · Journal of Biological Chemistry · 1945 · 73 citations · Full text

Life Sciences, Biochemistry, Pharmacology +5

Quantitative biochemical differences between tumor and host as a basis for cancer chemotherapy. V. Niacin and 6-aminonicotinamide.

Daniel M. Shapiro, L.S. Dietrich, Maurice E. Shils · PubMed · 1957 · 41 citations

Medicine, Oncology, Pharmacology +10