Antimetabolite-metabolite combination cancer chemotherapy.Effects of intra-arterial methotrexate—intramuscular citrovorum factor therapy in human cancer

The use of the nitrogen mustards in the palliative treatment of carcinoma.With particular reference to bronchogenic carcinoma

David A. Karnofsky, Walter H. Abelmann, Lloyd F. Craver et al. · Cancer · 1948 · 2.2K citations

Palliative Treatment, Medicine, Nitrogen Mustards +9

Temporary Remissions in Acute Leukemia in Children Produced by Folic Acid Antagonist, 4-Aminopteroyl-Glutamic Acid (Aminopterin)

Sidney Farber, Louis K. Diamond, Robert D. Mercer et al. · New England Journal of Medicine · 1948 · 1.8K citations

Hematological Malignancy, Temporary Remissions, Antibiotics +14

Fluorinated Pyrimidines, A New Class of Tumour-Inhibitory Compounds

Charles Heidelberger, P Danneberg, Dorothy Mooren et al. · Nature · 1957 · 1.6K citations

Medicinal Chemistry, Medicine, Fluorous Synthesis +5

FRACTIONATED INTRA-ARTERIAL CANCER. CHEMOTHERAPY WITH METHYL BIS AMINE HYDROCHLORIDE; A PRELIMINARY REPORT

Calvin T. Klopp, T. C. Alford, Jeanne C. Bateman et al. · Annals of Surgery · 1950 · 533 citations

Author Information, Literary Theory, Surgical Oncology +19

Clinical Evaluation of a New Antimetabolite, 6-Mercaptopurine, in the Treatment of Leukemia and Allied Diseases

Joseph H. Burchenal, M. Lois Murphy, Rose Ruth Ellison et al. · Blood · 1953 · 389 citations · Full text