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Neoplastic Characteristics of the DNA Found in the Plasma of Cancer Patients
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1989
Year
Genetic TestingDnaNormal ControlsEngineeringDna AnalysisPathologyNucleic Acid Amplification TestCancer PatientsTumor BiologyCarcinomaTumor HeterogeneityMolecular DiagnosticsRadiation OncologyCancer ResearchMedicineDna ReplicationCancer CellsDna FoundCell BiologyMalignant DiseaseNeoplastic CharacteristicsOncologyCancer Cell Dna
About one third of patients with various malignant diseases were found to have extractable amounts of DNA in their plasma whereas no DNA could be detected in normal controls. Using the test established by one of us (M.B.), which is based on decreased strand stability of cancer cell DNA, we have found that several plasma DNA originate from cancer cells.