The Blood Groups in Relation to Peptic Ulceration and Carcinoma of Colon, Rectum, Breast, and Bronchus

Abstract

We have previously shown an association between the ABO blood groups and cancer of the stomach, group A being significantly commoner in patients suffering from cancer of the stomach than in controls drawn from the same hospitals (Aird, Bentall, and Roberts, 1953). The further diseases for which fairly large numbers have so far been obtained are peptic ulceration and carcinoma of the colon, rectum, breast, and bronchus. The results are presented in this paper, which also includes some data on Rhesus grouping. In addition, further calculations have been made on the figures for cancer of the stomach already published. A detailed examination of our data follows. The results have proved remarkably clear-cut: blood group 0 is strikingly high and the other three groups correspondingly low in patients suffering from peptic ulcer. The three cancers now studied, unlike cancer of the stomach, showed no significant blood-group association.