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RADIORECEPTOR ASSAY FOR GROWTH HORMONE
252
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References
1973
Year
Animal PhysiologyGrowth HormoneHealth SciencesEndocrine MechanismHuman GrowthHuman Growth HormoneMedicinePhysiologyBioanalysisPlasma Membrane FragmentsEndocrinologyClinical ChemistryMetabolismPharmacologyEndocrine ResearchPregnant RabbitsRadiologyReproductive Endocrinology
ABSTRACT A sensitive radioreceptor assay (RRA) capable of detecting 0.2 ng of human growth hormone (hGH) has been developed using plasma membrane fragments derived from the liver of pregnant rabbits and 125I-hGH. Human, monkey, bovine and ovine GH all inhibit the binding of 125I-hGH, while the inhibition by hPL or human prolactin (hPRL) was minimal.