An Efficient and General Synthesis of Primary Amines by Ruthenium‐Catalyzed Amination of Secondary Alcohols with Ammonia

Abstract

Atom efficiency and selectivity are the key features of the first homogeneously catalyzed amination of secondary alcohols with ammonia to give the corresponding primary amines (see scheme). This novel amination method relies on the commercially available catalyst [Ru3(CO)12]/cataCXium PCy and does not require any additional source of hydrogen.