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Simultaneous microdetermination of bosentan, ambrisentan, sildenafil, and tadalafil in plasma using liquid chromatography/tandem mass spectrometry for pediatric patients with pulmonary arterial hypertension

HypertensionPulmonary Arterial HypertensionCardiovascular DiseaseMedicineAntihypertensive TherapyBioanalysisMass SpectrometryPediatric PatientsLaboratory MedicineAnalytical ChemistryClinical ChemistryPublic HealthPharmacologySimultaneous MicrodeterminationPulmonary Vascular DiseaseAnesthesiologyDrug Analysis