TRANSCAPILLARY MIGRATION OF HEAVY WATER AND THIOCYANATE ION IN THE PULMONARY CIRCULATION OF NORMAL SUBJECTS AND PATIENTS WITH CONGESTIVE HEART FAILURE 123

Abstract

During recent years numerous investigations have been concerned with the rates of transfer or exchange of various substances across capillary beds (1-6). These studies, by analyzing curves of disappearance over several minutes from ar- terial plasma of intravenously injected tracer sub- stances, have provided some information relative to all capillary beds combined. However, this type of experiment has not permitted a close analy- sis of the behavior of a substance during its first passage through a single organ capillary bed.