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Estimation of pr (a’x>>b’y) in the mnltiyariate normal case
32
Citations
7
References
1990
Year
Pharmacokinetic ModelingMedicineNon-independent Random VectorsBiostatisticsStatistical InferenceNeuroscienceProbability TheoryMnltiyariate Normal CaseMultivariate Normal DistributionStatistical SciencePharmacologyMathematical StatisticMaximum LikelihoodDrug Analysis
In this paper we consider two non-independent random vectors XpXi an i Vqxl having multivariate normal distribution and obtain the maximum likelihood and the minimum variance unbiased estimates of R=Pr (a′x>b′y) where a and b are two known vectors, The problem arises for example, in a system where the energy is supplied to the system by p sources and is consumed through q sources. Some interesting special cases are deduced. A simulation study was carried out to compare the MVUE and MLE of B.An application is provided to determine the effect of a certain drug on the level of biochemical compounds found in the brain.
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