Microsomal enzyme induction by methadone and its implications on tolerance to methadone lethality

Estimation of the ED50 and Its Error by Means of Logarithmic-Probit Graph Paper.

Louis W. Miller, M. L. Tainter · Experimental Biology and Medicine · 1944 · 1.1K citations

Social Sciences, Computer Science, Econometrics +5

BIOCHEMICAL AND PHARMACOLOGICAL CHANGES IN THE RAT FOLLOWING CHRONIC ADMINISTRATION OF MORPHINE, NALORPHINE AND NORMORPHINE

Joseph Cochin, Julius Axelrod · Journal of Pharmacology and Experimental Therapeutics · 1959 · 747 citations

Medicine, Pharmacology, Biochemical Pharmacology +16

SIMULTANEOUS QUANTITATIVE ASSESSMENT OF MORPHINE TOLERANCE AND PHYSICAL DEPENDENCE

E. Leong Way, Fu-Hsiung Shen · Journal of Pharmacology and Experimental Therapeutics · 1969 · 680 citations

Medicine, Pharmacokinetics, Pharmacology +10

THE ENZYMATIC N-DEMETHYLATION OF NARCOTIC DRUGS

Julius Axelrod · Journal of Pharmacology and Experimental Therapeutics · 1956 · 181 citations

Medicine, Pharmacology, Biochemical Pharmacology +12

Possible Mechanism of Tolerance to Narcotic Drugs

Julius Axelrod · Science · 1956 · 112 citations

Medicine, Medicinal Chemistry, Pharmacology +17