Concepedia

Genotoxic evaluation of pirfenidone using erythrocyte rodent micronucleus assay

Blanca Estela Alcántar‐Díaz, Belinda Claudia Gómez‐Meda, Guillermo Moisés Zúñiga‐González, Ana Lourdes Zamora-Pérez, J. González-Cuevas, Adriana Álvarez-Rodríguez, María Guadalupe Sánchez‐Parada, Jesús García‐Bañuelos, Juan Armendáriz‐Borunda

Food and Chemical Toxicology · 2012 · 11 citations · 21 references

DOI

Concepts

References

21

Antifibrotic action of pirfenidone and prednisolone: Different effects on pulmonary cytokines and growth factors in bleomycin-induced murine pulmonary fibrosis

Hisashi Oku, Toshikatsu Shimizu, Tomoji Kawabata et al. · European Journal of Pharmacology · 2008 · 438 citations

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In vivo rodent erythrocyte micronucleus assay. II. Some aspects of protocol design including repeated treatments, integration with toxicity testing, and automated scoring

Makoto Hayashi, James T. MacGregor, D. Gatehouse et al. · Environmental and Molecular Mutagenesis · 2000 · 241 citations

, , +16

ICH guideline S2 (R1) on genotoxicity testing and data interpretation for pharmaceuticals intended for human

Canary Wharf, E London · 2013 · 189 citations

, , +13

Pirfenidone effectively reverses experimental liver fibrosis

Ivan Hernández, Ana Sandoval-Rodríguez, Adriana Salazar et al. · Journal of Hepatology · 2002 · 170 citations

, , +11

The multifaceted role of pirfenidone and its novel targets

José Macías‐Barragán, Ana Sandoval-Rodríguez, José Navarro‐Partida et al. · Fibrogenesis & Tissue Repair · 2010 · 161 citations · Full text

, , +17