Chemical Communications · 2011 · 135 citations · 28 references
EngineeringBiotechnologyMaterials ScienceBiomaterialsBiosensorsEnzyme TechnologyDna BiosensorsEnzymatic BiosensorsEnzyme-based BiosensorsHydrogelsMetal Ion CatalysisMolecular SensorsDna NanobiosensorsDna SensorsDnazyme-based BiosensorsMetal Ion SensingNanomaterial-enabled BiosensorsNanoparticle-based ProbesSol - Gel TransitionSol-gel Transition
We propose the use of DNAzyme as a crosslinker of hydrogel to develop a catalytic platform for the sensing of metal ions. The DNAzyme crosslinked hydrogel can undergo gel-sol transition in response to Cu(2+) ions, which enables sensitive visual detection of Cu(2+) by observing the release of pre-trapped AuNPs.
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In vitro selection of RNA molecules that bind specific ligands
Andrew D. Ellington, Jack W. Szostak · Nature · 1990 · 9.7K citations
Enzyme-catalysed assembly of DNA hydrogel
Soong Ho Um, Jong Bum Lee, Nokyoung Park et al. · Nature Materials · 2006 · 873 citations