Palladium-catalyzed P(O)R₂ directed C–H arylation to synthesize electron-rich polyaromatic monophosphorus ligands

Abstract

Palladium-catalyzed arylation of (diisopropylphosphoryl)biphenyl skeleton derivatives by the P(O)R2 directed C-H functionalization was reported. The related products were obtained in high regioselectivity and good functional group tolerance was observed. This reaction provided a new and efficient pathway for the synthesis of polyaromatic monophosphorus ligands.