Cornea · 2004 · 29 citations · 4 references
MedicineInfectious DiseasesOphthalmologyImmunopathologyMedical MicrobiologyOcular MicrobiologyEyelid InfectionsEyelid UlcerationFungal Eye InfectionsFungal InfectionsInfectious Eye DiseaseScleral PathologyDermal UlcerationFungal ScleritisItraconazole TherapyOcular Surface Fungal InfectionScleral Fungal InfectionScleral Ulceration
PURPOSE: To describe a case of a scleral ulceration caused by Cryptococcus albidus in a patient with acquired immune deficiency syndrome (AIDS). DESIGN: Interventional case report. A 16-year-old girl with AIDS was admitted to the hospital with a 1-week history of cough, fever, and sudden onset of a painless scleral lesion on her left eye. Culture of the lesion revealed the fungus Crypotococcus albidus. RESULTS: The patient was treated with topical amphotericin B and systemic itraconazole, and she recovered fully over 4 weeks without sequelae. CONCLUSION: Cryptococcus albidus rarely causes disease in humans. It should be considered as a potential cause of ocular and systemic disease in patients with AIDS.
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Takashi Sugita, Masako Takashima, Reiko Ikeda et al. · Microbiology and Immunology · 2001 · 33 citations · Full text