Application of continuous‐flow liquid chromatography/fast‐atom bombardment mass spectrometry to the analysis of diagnostic acylcarnitines in human urine

Abstract

Acylcarnitine profiles of diagnostic value were generated from the equivalent of 0.1 microL of raw urine using the continuous-flow liquid chromatography/fast-atom bombardment mass spectrometry (LC/FAB-MS) interface for sample introduction. Further analysis was accomplished by gradient LC/MS using a commercially available packed fused-silica microbore column.