Human Cathelicidin Antimicrobial Peptide is Up-Regulated in the Eosinophilic Mucus Subgroup of Chronic Rhinosinusitis Patients

Abstract

This study shows expression of CAMP in nasal mucosa supporting its role in innate defenses against inhaled pathogens. Although CAMP mRNA was up-regulated in EMCRS patients, there were no statistically significant differences in protein levels in the nasal mucosa of EMCRS compared with CRS patients and controls.