Fragile genes as biomarkers: epigenetic control of WWOX and FHIT in lung, breast and bladder cancer

Methylation-specific PCR: a novel PCR assay for methylation status of CpG islands.

James G. Herman, Jeremy R. Graff, Sanna Myöhänen et al. · Proceedings of the National Academy of Sciences · 1996 · 5.7K citations

Life Sciences, Genetics, Molecular Biology +17

The FHIT Gene, Spanning the Chromosome 3p14.2 Fragile Site and Renal Carcinoma–Associated t(3;8) Breakpoint, Is Abnormal in Digestive Tract Cancers

Masataka Ohta, Hiroshi Inoue, M. Grazia Cotticelli et al. · Cell · 1996 · 997 citations · Full text

Life Sciences, Genetics, Molecular Genetics +10

Hypermethylation of the Death-Associated Protein (DAP) Kinase Promoter and Aggressiveness in Stage I Non-Small-Cell Lung Cancer

Xiaohui Tang · JNCI Journal of the National Cancer Institute · 2000 · 317 citations · Full text

Medicine, Molecular Biology, Oncology +15

Histone Deacetylase Inhibitors Have a Profound Antigrowth Activity in Endometrial Cancer Cells

Noriyuki Takai, Julian C. Desmond, T. Kumagai et al. · Clinical Cancer Research · 2004 · 240 citations

Medicine, Oncology, Pharmacology +14

<i>WWOX</i> : A candidate tumor suppressor gene involved in multiple tumor types

Adam J.W. Paige, Karen J. Taylor, Claire Taylor et al. · Proceedings of the National Academy of Sciences · 2001 · 218 citations · Full text

Medicine, Genetics, Molecular Genetics +14