Selective apoptosis of breast cancer cells by siRNA targeting of BORIS

A novel sequence-specific DNA binding protein which interacts with three regularly spaced direct repeats of the CCCTC-motif in the 5'-flanking sequence of the chicken c-myc gene.

Victor V. Lobanenkov, Robert H. Nicolas, Victor Adler et al. · PubMed · 1990 · 387 citations

BORIS, a novel male germ-line-specific protein associated with epigenetic reprogramming events, shares the same 11-zinc-finger domain with CTCF, the insulator protein involved in reading imprinting marks in the soma

Dmitri Loukinov, Elena M. Pugacheva, Sergei Vatolin et al. · Proceedings of the National Academy of Sciences · 2002 · 384 citations · Full text

Conditional Expression of the CTCF-Paralogous Transcriptional Factor BORIS in Normal Cells Results in Demethylation and Derepression of MAGE-A1 and Reactivation of Other Cancer-Testis Genes

Sergei Vatolin, Ziedulla Abdullaev, Svetlana Pack et al. · Cancer Research · 2005 · 200 citations

Spermatogenesis, Epigenetic Change, Genetics +22

Reciprocal Binding of CTCF and BORIS to the NY-ESO-1 Promoter Coincides with Derepression of this Cancer-Testis Gene in Lung Cancer Cells

Julie A. Hong, Kang Yang, Ziedulla Abdullaev et al. · Cancer Research · 2005 · 195 citations

Epigenetics, Tumor Biology, Reciprocal Binding +16

A widely expressed transcription factor with multiple DNA sequence specificity,CTCF, is localized at chromosome segment 16q22.1 within one of the smallest regions of overlap for common deletions in breast and prostate cancers

Galina N. Filippova, Annika Lindblom, Linda Meincke et al. · Genes Chromosomes and Cancer · 1998 · 143 citations

Genetics, Cancer Biology, Epigenetics +22