Determining hepatitis C genotype by analyzing the sequence of the NS5b region

CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice

Julie Thompson, Desmond G. Higgins, Toby J. Gibson · Nucleic Acids Research · 1994 · 64.9K citations · Full text

Life Sciences, Bioinformatics, Sequence Analysis +14

The neighbor-joining method: a new method for reconstructing phylogenetic trees.

Naruya Saitou, M Nei · Molecular Biology and Evolution · 1987 · 60.5K citations · Full text

Life Sciences, Bioinformatics, Evolutionary Biology +17

A simple method for estimating evolutionary rates of base substitutions through comparative studies of nucleotide sequences

Journal of Molecular Evolution · 1980 · 29.8K citations

Life Sciences, Biology, Evolutionary Biology +15

Peginterferon alfa-2b plus ribavirin compared with interferon alfa-2b plus ribavirin for initial treatment of chronic hepatitis C: a randomised trial

Michael P. Manns, John G. McHutchison, Stuart C. Gordon et al. · The Lancet · 2001 · 6.1K citations

Medicine, Internal Medicine, Pharmacotherapy +17

Interferon Alfa-2b Alone or in Combination with Ribavirin as Initial Treatment for Chronic Hepatitis C

John G. McHutchison, Stuart C. Gordon, Eugene R. Schiff et al. · New England Journal of Medicine · 1998 · 3.5K citations · Full text

Pharmacy, Pharmacotherapy, Hepatic Pharmacotherapy +16