Current Organic Chemistry · 2013 · 25 citations · 0 references
Natural SciencesChemistryCatalysisGreen ChemistryOrganic ChemistryMicrowave-assisted SynthesisOrganic SynthesisAlkylation ReactionsH-phosphonate SynthesisMicrowave-assisted AlkylationMicrowave-assisted Condensation ReactionsMicrowave-assisted EsterificationMicrowave-assisted Multicomponent ReactionsMicrowave-assisted Organic SynthesisPhosphide Synthesis
Depending on the conditions, the alcoholysis of simple dialkyl phosphites [(RO)2P(O)H] under microwave conditions may result in the formation of mixed derivative [(RO)(R’O)P(O)H] and the fully transesterified species [(R'O)2P(O)H] in different ratios. On one hand, this may be a method of choice for the preparation of less common dialkyl phosphites with alkyl chains of higher carbon atom number, on the other hand, the mixed derivatives are valuable building-blocks due to the chiral phosphorus atom. The thermal accomplishments led, in most cases, to uncomplete conversions. Keywords: Dialkyl phosphite, Dialkyl H-phosphonate, Alcoholysis, Transesterification, Microwave