ECL cell histamine mobilization and parietal cell stimulation in the rat stomach studied by microdialysis and electron microscopy

Abstract

As the histamine concentrations were higher in the tissue (microdialysate) than in blood, histamine seems to reach the parietal cells via the paracrine route. The fraction of active parietal cells seems to depend more on the age of the parietal cells than on the distance from the ECL cell.