Pharmacokinetics of S(+)- and R(−)-ibuprofen in volunteers and first clinical experience of S(+)-ibuprofen in rheumatoid arthritis

CLINICAL STUDIES WITH AN ARTICULAR INDEX FOR THE ASSESSMENT OF JOINT TENDERNESS IN PATIENTS WITH RHEUMATOID ARTHRITIS

Dorothy M. Ritchie, James Boyle, John M. Mcinnes et al. · QJM · 1968 · 1.4K citations

Medicine, Orthopaedic Surgery, Musculoskeletal Medicine +8

Pharmacological differences between the optical isomers of ibuprofen: evidence for metabolic inversion of the (—)-isomer

S. S. Adams, P. Bresloff, C. G. Mason · Journal of Pharmacy and Pharmacology · 1976 · 386 citations

Medicine, Medicinal Chemistry, Pharmacology +6

Stereoselective disposition of ibuprofen enantiomers in man.

EJ Lee, K. Williams, Richard O. Day et al. · British Journal of Clinical Pharmacology · 1985 · 257 citations · Full text

Medicine, Pharmacokinetics, Pharmacology +8

Stereoselective disposition of ibuprofen enantiomers in infants.

Enrique Rey, Ann Pariente‐Khayat, L Gouyet et al. · British Journal of Clinical Pharmacology · 1994 · 213 citations · Full text

Medicine, Pharmacokinetics, Pharmacology +9

Isomeric inversion of ibuprofen (r)‐enantiomer in humans

David G. Kaiser, Garrett J. Vangiessen, Robert J. Reischer et al. · Journal of Pharmaceutical Sciences · 1976 · 191 citations

Medicine, Medicinal Chemistry, Pharmacology +9