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Coexistence of the loss of heterozygosity at the PTEN locus and HER2 overexpression enhances the Akt activity thus leading to a negative progesterone receptor expression in breast carcinoma

Akt ActivityBreast OncologyHormonal ReceptorGynecologyBreast CancerBreast CarcinomaCell BiologyTumor SuppressorPten LocusEndocrinologyMedicineRadiation OncologyCell SignalingTumor BiologyEndocrine-related Cancer