PROGNOSTI IMPLICATIONS OF PIGMENT EPITHELIAL DETACHMENT IN BEVACIZUMAB (AVASTIN)-TREATED EYES WITH AGE-RELATED MACULAR DEGENERATION AND CHOROIDAL NEOVASCULARIZATION

Abstract

Despite monthly intravitreal bevacizumab injections for neovascular AMD patients with a large component PED, the majority had minimal to no response of the PED. Sub- and intraretinal fluid response was faster in neovascular AMD without large PEDs, but after 7 months, vision change and reabsorption of intra- and subretinal fluid were similar in the two groups. Sub- and intraretinal fluid response did not appear to be related to PED size. Bevacizumab was very effective in reducing more of the sub- and intraretinal fluid than the PED fluid in AMD with CNV.