The Journal of Clinical Endocrinology & Metabolism · 1978 · 52 citations · 0 references
MedicineEndocrinologyPharmacologyDiabetologyMetabolic RegulationDiabetes MellitusPancreatic DiseasesPancreatic DisordersPancreatic EndocrinologyPancreatic HormonesPancreatic PathologyEndocrine Pancreatic FunctionPancreatic Endocrine DisordersPancreatic Endocrine DysfunctionPancreatic Hormone SecretionPancreatic Islet FunctionPancreatic Islet SecretionPancreatic Polypeptide PhysiologyPancreatic Secretion
In patients with chronic pancreatitis, the plasma pancreatic polypeptide (PP) response to insulininduced hypoglycemia is impaired, although basal levels are within the normal range. Somatostatin lowers the PP response in normal people and in patients with chronic pancreatitis. The PP response may be a useful index of pancreatic function.