Publication | Closed Access
Channel‐Type Molecular Structures. Part 2. Synthesis of Bouquet‐Shaped Molecules Based on a β‐Cyclodextrin Core
62
Citations
15
References
1992
Year
Membrane StructureSupramolecular AssemblyLipid BiophysicsEngineeringOrganic ChemistryChannel‐type MoleculesNew SeriesChemistryPolymersMacromolecular EngineeringPotential Transmembrane StructuresBiophysicsBouquet‐shaped MoleculesMembrane BiologyMembrane Systemβ‐Cyclodextrin CoreBiomolecular EngineeringHost-guest ChemistryMembrane FormationMembrane BiophysicsChannel‐type Molecular StructuresCyclodextrin ProductionPolymer ScienceAmphiphilic SystemMedicine
Abstract A new series of channel‐type molecules presenting the features of potential transmembrane structures is described. They result from the grafting of amphiphilic side chains on a β‐cyclodextrin derivative 3 that constitutes the organizing core. They belong to the ‘bouquet’ family ( B ). Compounds bearing poly(oxyethylene) side chains, B 16 and 17 , and their polymethylene analogues B 18 and 19 , were synthesized. The properties investigated emphasize the suitability of such molecules to be incorporated into lipid bilayer membranes.
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