Synthese von 2‐Thia‐6‐aza‐adamantan und Derivaten

Abstract

Abstract The synthesis of 2‐thia‐6‐aza‐adamantane ( 19 ) and several of its derivatives was achieved starting from 9‐azabicyclo[3.3.1]nona‐2,6‐diene ( 9 ) which was prepared from cis, cis ‐cycloocta‐1, 5‐diene ( 1 ). Transannular addition of sulfur dichloride to its N‐benzenesulfonyl and N‐formyl derivatives 10 and 11 yielded the tricyclic dichlorides 12 and 13 , respectively; the 2‐thia‐6‐aza‐adamantanes 14–19 were synthesized from 13 .