Platelet-activating factor induced calcium mobilization and phosphoinositide metabolism in cultured bovine cerebral microvascular endothelial cells

A new generation of Ca2+ indicators with greatly improved fluorescence properties.

Grzegorz Grynkiewicz, Martin Poenie, Roger Y. Tsien · Journal of Biological Chemistry · 1985 · 21.7K citations · Full text

Inositol trisphosphate, a novel second messenger in cellular signal transduction

Michael J. Berridge, Robin F. Irvine · Nature · 1984 · 6.1K citations

Signal Transduction, Biochemistry, Natural Sciences +9

Lithium amplifies agonist-dependent phosphatidylinositol responses in brain and salivary glands

Michael J. Berridge, C. Peter Downes, Michael R. Hanley · Biochemical Journal · 1982 · 2.1K citations · Full text

Neurotransmitter, Salivary Gland, Experimental Pharmacology +19

The inositol tris/tetrakisphosphate pathway—demonstration of Ins(l,4,5)P3 3-kinase activity in animal tissues

Robin F. Irvine, Amber Letcher, John P. Heslop et al. · Nature · 1986 · 706 citations

Molecular Physiology, Signal Transduction, Biochemistry +13

Platelet-activating factor, a new mediator of anaphylaxis and immune complex deposition from rabbit and human basophils

Jacques Benveniste · Nature · 1974 · 279 citations

Inflammation, Thrombopoiesis, Allergy +12