Oral-facial-digital syndrome.

Abstract

Papillon-Leage and Psaume in 1954 reported a 'hereditary malformation of the buccal mucous membrane, and abnormal frena' (Papillon-Leage and Psaume, 1954a). Other French and German authors have since published full accounts of this condition, and Gorlin and Pindborg (1964) have summarized current knowledge of the syndrome in a recent textbook. They described it under the heading of orodigitofacial dystosis, but as there is involvement of other tissues than bone the term oral-facial-digital (OFD) syndrome is to be preferred (Doege, Thuline, Priest, Norby, and Bryant, 1964).