Treatment of Streptozotocin-Induced Diabetes Mellitus in Rats by Transplantation of Islet Cells from Two Major Histocompatibility Complex Disparate Rats in Combination with Intra Bone Marrow Injection of Allogeneic Bone Marrow Cells

Abstract

The transplantation of PIs from two MHC-disparate donors was completely achieved in combination with IBM-BMT, resulting in the improvement of blood glucose levels and the amelioration of diabetes mellitus.