Organocatalytic Asymmetric Synthesis of Tetracyclic Pyridocarbazole Derivatives by Using a Diels–Alder/aza‐Michael/Aldol Condensation Domino Reaction

Abstract

Triple domino: An organocatalytic asymmetric triple cascade reaction to form tetracyclic pyridocarbazole derivatives is described. The new protocol includes a Diels–Alder/aza-Michael/aldol condensation sequence. Up to six stereogenic centers are formed with excellent diastereo- and enantioselectivity. IM = iminium activation; EN = enamine activation. As a service to our authors and readers, this journal provides supporting information supplied by the authors. Such materials are peer reviewed and may be re-organized for online delivery, but are not copy-edited or typeset. Technical support issues arising from supporting information (other than missing files) should be addressed to the authors. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.